Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Developed biosensors for the detection of coronaviruses.

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Luciferase, Protein-Protein interactions

Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Various type of the biosensors for SARS-CoV-2 virus detection . A) CRISPR based nucleic acid (RNA) detection . B) FET based biosensor operation , C) AuNPs based FTO electrode biosensor , D) Surface Plasmon Resonance (SPR) based biosensor, E) 2D gold Nano-islands (AuNIs) functionalized biosensors .

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Virus, CRISPR, RNA Detection, SPR Assay

Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Illustration of proposed SPR based biosensor for detection of coronaviral surface antigen (SCVme), AFM images of the sequential binding of GBP-E-SCVme and anti-SCVme on the gold-micro-patterned surface. (A) Bare gold surface, (B) binding of the GBP-E-SCVme fusion proteins onto the gold surface, and (C) subsequent binding of the anti-SCVme antibodies on the GBP-E-SCVme layer. Left, representation plans for the successive binding of GBP-E-SCVme and anti-SCVme on the gold micro-patterns; middle, three-dimensional topological images; right, the cross-sectional contours of samples a–c, sequentially (these are average height differences of the individual scan lines from each area) .

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Binding Assay

Journal: Npj Biosensing

Article Title: Plasmonic biosensors and actuators for integrated point-of-care diagnostics

doi: 10.1038/s44328-025-00050-1

Figure Lengend Snippet: a Biacore SPR sensor chip provides real-time, ready-to-go analysis of a wide range of molecular interactions, providing kinetics, affinity, and binding data (Credit: Cytiva Life Sciences (cytivalifesciences.com)). b Carterra SPR sensors integrate with HT-SPR technology, enabling fragments and small molecules screening and antibody discovery. c Detection principle of NG-Test CARBA 5 Lateral Flow Assay, NG Biotech. Reprinted with permission from ref. . Copyright 2018 Oxford Academic. d Principle of detection method for Nucleic Acid Lateral Flow Immunoassay (NALFIA), Pocket Diagnostic. Reprinted with permission from ref. . Copyright 2024 Springer Nature. e Klarite SERS substrate on an array of inverted pyramid structures (credit: optics.org). Reprinted with permission from ref. . Copyright 2011 Applied Spectroscopy. f Commercial Ocean Insight SERS substrate made of gold or silver, mounted in a microscope slide. Reprinted with permission from ref. . Copyright 2023 Springer Nature. g Nanopartz Plasmonic PCR and its 8-channels for POC system (credit: Nanopartz Inc. (nanopartz.com)). h Nexless P – IV transforms is an innovative Plasmonic PCR Technology, combining advanced plasmonic gold nanorod nanoparticles with real-time quantitative PCR. (Credit: Nexless Healthcare (nexlesshealthcare.ca)).

Article Snippet: Biacore SPR biosensors are designed with three core technologies: an optical detector system, a 50-nm layer of gold on the sensor chip, a microfluidic chip and liquid handling system .

Techniques: Binding Assay, Lateral Flow Assay, Diagnostic Assay, Spectroscopy, Microscopy, Real-time Polymerase Chain Reaction